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EC Number Localization Commentary GeneOntology No. Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.11.1nucleus - GO:0005634 AmiGO QuickGO -, 666313, 666421, 682395, 714695, 716398, 716689
Display the word mapDisplay the reaction diagram Show all sequences 3.1.11.1nucleus EXO1 is bound to CtIP GO:0005634 AmiGO QuickGO 714833
Display the word mapDisplay the reaction diagram Show all sequences 3.1.11.1nucleus in S-phase cells both hEXO1 isoforms accumulate in proliferating cell nuclear antigen-positive foci. After UV irradiation of cells both hEXO1a and hEXO1b accumulated similarly at local UV-induced DNA damages, LUDS, colocalizing with NER preincision factors. Inhibition of repair synthesis enhances hEXO1 accumulation at LUDs GO:0005634 AmiGO QuickGO 716779
Display the word mapDisplay the reaction diagram Show all sequences 3.1.11.1nucleus sub-nuclear localization of hEXO1 in replication foci during S-phase progression and in response to laser-induced DNA double strand breaks, hEXO1 is rapidly recruited to DNA double strand breaks, mechanism, overview. Co-localization with proliferating cell nuclear antigen. Mapping of region on hEXO1 required for recruitment to DNA double strand breaks GO:0005634 AmiGO QuickGO 714811
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