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Search term: lysosome

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EC Number Recommended Name Localization Commentary GeneOntology No. Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.1631,6-alpha-D-mannosidase lysosome - GO:0005764 AmiGO QuickGO 171768, 673892, 674494, 706628
Display the reaction diagram Show all sequences 3.2.1.1271,6-alpha-L-fucosidase lysosome - GO:0005764 AmiGO QuickGO 663840
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.671-phosphatidylinositol 4-kinase lysosome membrane GO:0005764 AmiGO QuickGO 641789
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1501-phosphatidylinositol-3-phosphate 5-kinase lysosome - GO:0005764 AmiGO QuickGO 761580
Display the reaction diagram Show all sequences 2.4.99.202'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase lysosome - GO:0005764 AmiGO QuickGO 727868
Show all pathways known for 2.5.1.39Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.394-hydroxybenzoate polyprenyltransferase lysosome - GO:0005764 AmiGO QuickGO 636997
Show all pathways known for 3.1.3.5Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.55'-nucleotidase lysosome - GO:0005764 AmiGO QuickGO 95024, 95029
Show all pathways known for 3.1.2.1Display the word mapDisplay the reaction diagram Show all sequences 3.1.2.1acetyl-CoA hydrolase lysosome - GO:0005764 AmiGO QuickGO 94471
Show all pathways known for 3.1.3.2Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.2acid phosphatase lysosome - GO:0005764 AmiGO QuickGO -, 134700, 134719, 134729, 134750, 134758, 652665, 664547, 706063
Show all pathways known for 3.1.3.2Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.2acid phosphatase lysosome enzyme type B is localized to the organelles, presumably lysosomes, in both soluble form and membrane-bound form GO:0005764 AmiGO QuickGO 134703
Show all pathways known for 3.1.3.2Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.2acid phosphatase lysosome membrane GO:0005764 AmiGO QuickGO 134694, 134697, 134738
Show all pathways known for 3.1.2.20Display the word mapDisplay the reaction diagram Show all sequences 3.1.2.20acyl-CoA hydrolase lysosome - GO:0005764 AmiGO QuickGO 646190
Display the word mapDisplay the reaction diagram Show all sequences 3.6.2.1adenylylsulfatase lysosome - GO:0005764 AmiGO QuickGO 289087, 289089, 289090
Show all pathways known for 3.2.1.28Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.28alpha,alpha-trehalase lysosome intestinal and muscle acid acid trehalases GO:0005764 AmiGO QuickGO 665118
Show all pathways known for 3.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.1alpha-amylase lysosome isoenzymes alpha-I1 and alpha-I2 and muscle alpha-amylase GO:0005764 AmiGO QuickGO 654030
Show all pathways known for 3.2.1.22Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.22alpha-galactosidase lysosome - GO:0005764 AmiGO QuickGO 171218, 171240, 704691, 705734, 729607, 730674, 750344, 751953
Show all pathways known for 3.2.1.22Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.22alpha-galactosidase lysosome recombinant enzyme expressed in COS-7 cell GO:0005764 AmiGO QuickGO 696400
Show all pathways known for 3.2.1.20Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.20alpha-glucosidase lysosome - GO:0005764 AmiGO QuickGO -, 393275, 393317, 393323, 393325, 393327, 393336, 681105, 694198, 707102
Show all pathways known for 3.2.1.20Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.20alpha-glucosidase lysosome acid alpha-glucosidase I and II GO:0005764 AmiGO QuickGO 393342
Show all pathways known for 3.2.1.51Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.51alpha-L-fucosidase lysosome - GO:0005764 AmiGO QuickGO 208701, 208704, 208705, 208729, 208733, 208737, 739213, 750767
Show all pathways known for 3.2.1.24Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.24alpha-mannosidase lysosome - GO:0005764 AmiGO QuickGO 136006, 136007, 656517, 656592, 656805, 664603, 665065, 729814, 750617, 751574
Show all pathways known for 3.2.1.24Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.24alpha-mannosidase lysosome alpha-D-mannosidase exists in multiple forms, which are detectable in most human tissues GO:0005764 AmiGO QuickGO 681902
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.49alpha-N-acetylgalactosaminidase lysosome - GO:0005764 AmiGO QuickGO 208665, 665838, 709530
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.50alpha-N-acetylglucosaminidase lysosome - GO:0005764 AmiGO QuickGO 208677, 208678, 208687, 665908, 666847, 679282, 681949, 694897, 709965, 751986
Show all pathways known for 3.5.1.4Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.4amidase lysosome - GO:0005764 AmiGO QuickGO 686040
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.1arylsulfatase (type I) lysosome - GO:0005764 AmiGO QuickGO 135532, 693036, 707966, 709618, 709667, 709806, 730069
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.1arylsulfatase (type I) lysosome 63-kDa single-chain precursor protein localizes to pre-lysosomal compartments and tightly associates with organelle membranes. Proteolytically processed arylsulfatase G fragments of 34-, 18-, and 10-kDa are found in lysosomal fractions and lost their membrane association. Lysosomal transport of arylsulfatase G in the liver is independent of mannose 6-phosphate, sortilin, and Limp2. Mutation of glycosylation site N497 abrogates transport to lysosomes, due to impaired mannose 6-phosphate modification GO:0005764 AmiGO QuickGO 730056
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.1arylsulfatase (type I) lysosome inside membrane-bound cytoplasmic vesicles GO:0005764 AmiGO QuickGO 681811
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.1arylsulfatase (type I) lysosome inside membrane-bound cytoplasmic vesicles distributed throughout the cell body GO:0005764 AmiGO QuickGO 681811
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.1arylsulfatase (type I) lysosome protein carries mannose 6-phosphate, indicating lysosomal sorting GO:0005764 AmiGO QuickGO 730022
Display the word mapDisplay the reaction diagram Show all sequences 7.2.1.3ascorbate ferrireductase (transmembrane) lysosome - GO:0005764 AmiGO QuickGO 389971, 673552
Display the word mapDisplay the reaction diagram Show all sequences 7.2.1.3ascorbate ferrireductase (transmembrane) lysosome LCytb GO:0005764 AmiGO QuickGO 744757
Display the word mapDisplay the reaction diagram Show all sequences 7.4.2.5bacterial ABC-type protein transporter lysosome - GO:0005764 AmiGO QuickGO 670487, 687663, 710640, 734330
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.167baicalin-beta-D-glucuronidase lysosome - GO:0005764 AmiGO QuickGO 712143
Display the reaction diagram Show all sequences 3.2.2.11beta-aspartyl-N-acetylglucosaminidase lysosome - GO:0005764 AmiGO QuickGO 171768
Show all pathways known for 3.2.1.23Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.23beta-galactosidase lysosome - GO:0005764 AmiGO QuickGO 171133, 171271, 697390
Show all pathways known for 3.2.1.21Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.21beta-glucosidase lysosome - GO:0005764 AmiGO QuickGO 326291, 326358, 664628, 664633
Show all pathways known for 3.2.1.31Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.31beta-glucuronidase lysosome - GO:0005764 AmiGO QuickGO 26856, 26862, 26864, 26866, 26867, 26872, 26873, 26876, 26877, 708528, 708531, 739626
Show all pathways known for 3.2.1.31Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.31beta-glucuronidase lysosome beta-glucuronidase is present in every compartment of the digestive cell endo-lysosomal compartment and appears to be not necessarily membrane-bound. Enzyme is released to the digestive alveolar lumen in secretory lysosomes produced by basophilic cells and endocytosed by digestive cells GO:0005764 AmiGO QuickGO 697191
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.25beta-mannosidase lysosome - GO:0005764 AmiGO QuickGO 136027, 136032, 136035, 136045, 136050, 136056
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.25beta-mannosidase lysosome goat liver contains both an acid lysosomal beta-mannosidase, deficient in beta-mannosidosis, and a neutral nonlysosomal beta-mannosidase GO:0005764 AmiGO QuickGO 136036
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.53beta-N-acetylgalactosaminidase lysosome - GO:0005764 AmiGO QuickGO 136606
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.52beta-N-acetylhexosaminidase lysosome - GO:0005764 AmiGO QuickGO 393661, 393680, 393689, 393690, 393691, 393693, 393694, 393700, 393702, 393709, 654795, 679278, 707729, 751281
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.52beta-N-acetylhexosaminidase lysosome in healthy humans GO:0005764 AmiGO QuickGO 393664
Show all pathways known for 6.3.5.5Display the word mapDisplay the reaction diagram Show all sequences 6.3.5.5carbamoyl-phosphate synthase (glutamine-hydrolysing) lysosome coexpression of small GTPase Rheb with CAD leads to increased accumulation of CAD on lysosomes GO:0005764 AmiGO QuickGO 745319
Show all pathways known for 3.1.1.1Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.1carboxylesterase lysosome - GO:0005764 AmiGO QuickGO 170986
Display the word mapDisplay the reaction diagram Show all sequences 3.4.16.5carboxypeptidase C lysosome - GO:0005764 AmiGO QuickGO -, 665905, 680391, 698164, 703982, 708470
Display the word mapDisplay the reaction diagram Show all sequences 3.4.16.5carboxypeptidase C lysosome in transfected HEK-293 cells GO:0005764 AmiGO QuickGO 699085
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 lysosome - GO:0005764 AmiGO QuickGO -, 697180, 708598
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 lysosome inactive proenzyme GO:0005764 AmiGO QuickGO 691461
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome - GO:0005764 AmiGO QuickGO -, 36619, 36627, 36634, 36646, 36651, 649642, 668520, 669158, 669599, 678362, 678699, 678977, 679023, 680996, 681398, 695447, 696631, 698029, 699130, 699198, 699208, 699337, 699449, 699485, 699729, 700456, 707625, 707967, 707971, 708033, 708035, 708217, 708219, 708258, 708264, 708275, 708277, 708376, 708482, 708598, 708638, 708641, 709116, 709347, 709368, 709396, 709745, 709771, 709916, 709979, 710021, 710205, 710254, 752900, 753002, 753382, 753558, 753603, 753604, 754582, 755530
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome acidic GO:0005764 AmiGO QuickGO 669985
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome cathepsin B is an endo-lysosomal cysteine protease GO:0005764 AmiGO QuickGO 696544
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome cathepsin B is expressed ubiquitously and represents the major portion of lysosomal enzymes GO:0005764 AmiGO QuickGO 709922
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome cathepsin B is synthesised as a pre-pro-enzyme and the primary pathways for its normal trafficking to the lysosome utilise mannose-6-phosphate receptors. Inactive pro-cathepsin-B is processed to active single and double chain forms of cathepsin-B in the late endosomes and lysosomes, respectively GO:0005764 AmiGO QuickGO 698146
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome in oxidative stress cathepsin B may be released from lysosomes into cytoplasm with lowered pH and cleave cytoplasmic proteins, including caspase-3 substrates GO:0005764 AmiGO QuickGO 678362
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome intracellular localization GO:0005764 AmiGO QuickGO 698014
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome lysosomes localized at podosomes GO:0005764 AmiGO QuickGO 697099
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome phagocytosis of crystalline silica induces lysosomal destabilization and subsequent release of cathepsin B into the cytoplasm, leading to NALP3 activation GO:0005764 AmiGO QuickGO 707393
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome predominantly GO:0005764 AmiGO QuickGO 696527
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B lysosome stress stimulated secretion from the lysosomes GO:0005764 AmiGO QuickGO 753138
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B6cathepsin B-like protease lysosome - GO:0005764 AmiGO QuickGO 664706, 666453, 679598, 732089
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.5cathepsin D lysosome - GO:0005764 AmiGO QuickGO 36919, 36935, 36952, 36953, 36958, 679068, 695420, 696009, 696295, 696402, 697479, 697723, 698022, 699114, 700090, 700128, 711326, 711354, 711855, 711892, 712050, 712160, 713125, 717517, 717631, 718306, 731091, 731168, 731411, 731454, 731700, 731831, 731928, 732059, 752655, 753609, 753730, 754306, 754432, 754635, 755429, 755464, 755627
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.5cathepsin D lysosome the mature form of cathepsin D is located at lysosome GO:0005764 AmiGO QuickGO 713109
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.34cathepsin E lysosome Cat E is partially present in lysosomes GO:0005764 AmiGO QuickGO 677990
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.41cathepsin F lysosome - GO:0005764 AmiGO QuickGO 137259, 137265, 670246, 683112, 698507, 698512, 700574, 731340, 753610
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.20cathepsin G lysosome - GO:0005764 AmiGO QuickGO 36500, 36501, 665912, 709353
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.20cathepsin G lysosome derived from primary murine microglia GO:0005764 AmiGO QuickGO 683531
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.20cathepsin G lysosome microglia-derived GO:0005764 AmiGO QuickGO 683531
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.16cathepsin H lysosome - GO:0005764 AmiGO QuickGO -, 638826, 680794, 732111, 752928, 753866, 753961, 754606, 755176, 755375
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.16cathepsin H lysosome biosynthesis in endoplasmic reticulum, proteolytic cleavage of proenzyme during translocation to lysosomes GO:0005764 AmiGO QuickGO 638819
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.38cathepsin K lysosome - GO:0005764 AmiGO QuickGO -, 30362, 696041, 696617, 696631, 696654, 696664, 696697, 697011, 697012, 697066, 697257, 697375, 697619, 700688, 700689, 701180, 701297, 707334, 708260, 708423, 708450, 708689, 710231, 732741, 753618
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.15cathepsin L lysosome - GO:0005764 AmiGO QuickGO 647912, 647920, 647927, 647930, 669158, 678515, 678782, 680861, 681907, 707640, 710810, 711055, 711939, 712089, 712140, 713010, 713155, 717223, 752853, 753343, 753545, 753565, 753596, 755110
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.15cathepsin L lysosome mature cathepsin L GO:0005764 AmiGO QuickGO 712921
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.15cathepsin L lysosome the pro-enzyme is normally activated in the acidic environment of lysosomes GO:0005764 AmiGO QuickGO 711349
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B49cathepsin L1 lysosome - GO:0005764 AmiGO QuickGO 753379
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B60cathepsin L2 lysosome - GO:0005764 AmiGO QuickGO -, 753117
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.42cathepsin O lysosome - GO:0005764 AmiGO QuickGO 137267
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B65cathepsin P lysosome cathepsin P co-localizes with cathepsin B and may function in an endosomal-lysosomal compartment GO:0005764 AmiGO QuickGO 700693
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.27cathepsin S lysosome - GO:0005764 AmiGO QuickGO -, 30359, 647951, 647986, 667971, 667984, 668479, 669716, 677874, 678517, 678663, 680995, 682132, 682236, 682543, 692671, 696638, 696995, 697041, 697683, 698325, 698859, 699442, 701382, 710217, 753701, 753917
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.27cathepsin S lysosome the enzyme contains a signal peptide (residues 1-17) GO:0005764 AmiGO QuickGO 753606
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.24cathepsin T lysosome - GO:0005764 AmiGO QuickGO 30136, 30140, 665093
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43cathepsin V lysosome - GO:0005764 AmiGO QuickGO 717374, 732591, 752678, 753117, 754753
Display the word mapDisplay the reaction diagram Show all sequences 3.4.18.1cathepsin X lysosome - GO:0005764 AmiGO QuickGO 36443, 36444, 679023, 683222, 683448, 683533, 684099, 696995, 708023, 708056, 708373, 710431, 753477
Display the word mapDisplay the reaction diagram Show all sequences 3.4.18.1cathepsin X lysosome multivesicular bodies and lipofuscin granules GO:0005764 AmiGO QuickGO 683448
Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.26CDP-diacylglycerol diphosphatase lysosome - GO:0005764 AmiGO QuickGO 210005
Show all pathways known for 3.5.1.23Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.23ceramidase lysosome - GO:0005764 AmiGO QuickGO 171991, 668638, 696396, 700316, 719536, 733395, 734696, 752968, 753491, 753570, 754849, 754939, 754949
Show all pathways known for 3.5.1.23Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.23ceramidase lysosome acid ceramidase GO:0005764 AmiGO QuickGO 711799, 719197
Show all pathways known for 3.5.1.23Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.23ceramidase lysosome CDase is distributed with late endosomes/lysosomes in hepatocytes GO:0005764 AmiGO QuickGO 656010
Show all pathways known for 3.5.1.23Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.23ceramidase lysosome of hepatocytes GO:0005764 AmiGO QuickGO 733408
Show all pathways known for 3.5.1.23Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.23ceramidase lysosome predominantly GO:0005764 AmiGO QuickGO 711949
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.8cerebroside-sulfatase lysosome - GO:0005764 AmiGO QuickGO 135511, 135666, 135667, 135668, 135669, 135670, 135671, 135672, 135674, 135676, 135677, 135679, 135680, 135681, 135682, 135683, 135684, 135685, 135686, 135687, 649289, 652443, 691881, 692081, 693260, 708615, 708623, 708662, 714958
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.14chitinase lysosome secretory GO:0005764 AmiGO QuickGO 664449
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.1chymotrypsin lysosome - GO:0005764 AmiGO QuickGO 680927
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.1chymotrypsin lysosome chymotrypsin colocalizes with the lysosomal marker protein LAMP1 GO:0005764 AmiGO QuickGO 732856
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.51cruzipain lysosome - GO:0005764 AmiGO QuickGO -, 638879, 698164, 698293, 718182, 732673
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.51cruzipain lysosome isoform 1 GO:0005764 AmiGO QuickGO 696523
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3cystinyl aminopeptidase lysosome - GO:0005764 AmiGO QuickGO 35902, 35918
Display the word mapDisplay the reaction diagram Show all sequences 1.6.2.2cytochrome-b5 reductase lysosome - GO:0005764 AmiGO QuickGO 724801
Display the word mapDisplay the reaction diagram Show all sequences 3.1.22.1deoxyribonuclease II lysosome - GO:0005764 AmiGO QuickGO -, 134302, 134305, 134308, 651415, 682740, 713781
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