EC Number |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference |
---|
3.1.4.3 | -999 |
- |
more |
kinetic parameters depend on the physicochemical properties of substrate aggregates. Larger micelles with a ratio bile salt/lipid smaller than 5 show higher activity and shorter steady state duration of less than 4 min, smaller micelles with a ratio bile salt/lipid greater than 5 show lower activity and longer steady state of about 10 min |
678721 |
3.1.4.3 | 0.016 |
1.2 |
lecithin |
- |
135298 |
3.1.4.3 | 0.025 |
- |
1-palmitoyl-lysophosphatidylcholine |
pH 7.5, 37°C |
652656 |
3.1.4.3 | 0.03 |
- |
diheptanoylphosphatidylcholine |
micellar substrate, wild-type PLC |
135281 |
3.1.4.3 | 0.0513 |
- |
L-alpha-lysophosphatidylcholine |
pH 5.0, 37°C |
751137 |
3.1.4.3 | 0.087 |
- |
phosphatidylinositol |
PLC-beta1a, 2mM free Ca2+ |
135288 |
3.1.4.3 | 0.09 |
- |
sphingomyelin |
pH 7.5, 37°C |
652656 |
3.1.4.3 | 0.137 |
- |
phosphatidylinositol 4,5-bisphosphate |
PLC-beta1a, 2mM free Ca2+ |
135288 |
3.1.4.3 | 0.165 |
- |
1-palmitoyl-lysophosphatidylcholine |
Vmax 89 nmol/min mg |
665632 |
3.1.4.3 | 0.166 |
- |
1,2-dipalmitoylphosphatidylcholine |
- |
135289 |