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EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Reference
2.5.1.22
-999
-
more
ratio of kcat/Km value of wild-type is 40000 for substrate spermidine, and 71000000 for S-adenosyl-L-methioninamine, respectively
687717
2.5.1.22
0.0001
-
S-adenosylmethioninamine
-
489873
2.5.1.22
0.0005
-
S-adenosyl 3-(methylthio)propylamine
wild type enzyme, at pH 7.5 and 37°C
739393
2.5.1.22
0.00054
-
7,7-Difluorospermidine
-
489869
2.5.1.22
0.0006
-
S-adenosylmethioninamine
-
489863
,
489864
,
489875
2.5.1.22
0.0009
-
S-adenosyl 3-(methylthio)propylamine
mutant enzyme S165D/L175E/T178H/C206R, at pH 7.5 and 37°C
739393
2.5.1.22
0.001
-
S-adenosylmethioninamine
-
489868
2.5.1.22
0.0011
-
7-Monofluorospermidine
-
489869
2.5.1.22
0.005
-
S-adenosylmethioninamine
-
489862
2.5.1.22
0.006
-
spermidine
-
489863
,
489864
,
489873
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