EC Number |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference |
---|
1.2.1.104 | -999 |
- |
more |
kinetic and thermodynamic analysis |
654615 |
1.2.1.104 | -999 |
- |
more |
kinetic study, reaction of pyruvate dehydrogenase complex |
656580 |
1.2.1.104 | 0.00008 |
- |
thiamine diphosphate |
whole enzyme complex |
348925 |
1.2.1.104 | 0.0002 |
- |
pyruvate |
2-oxoglutarate dehydrogenase complex, pH 7.6, 30°C, in presence of thiamine diphosphate, in presence of 2 mM Mn2+ |
656580 |
1.2.1.104 | 0.0005 |
- |
CoA |
pH 7.4, 30°C |
759746 |
1.2.1.104 | 0.0006 |
- |
pyruvate |
2-oxoglutarate dehydrogenase complex, pH 7.6, 30°C, in presence of thiamine diphosphate, in presence of 2 mM Ca2+ |
656580 |
1.2.1.104 | 0.0006 |
- |
pyruvate |
cooperativity is observed, Hill coefficient is 1.6, pH 7.6, 37°C |
758852 |
1.2.1.104 | 0.0007 |
- |
pyruvate |
2-oxoglutarate dehydrogenase complex, pH 7.6, 30°C, in absence of thiamine diphosphate, in presence of 2 mM Mn2+ |
656580 |
1.2.1.104 | 0.00158 |
- |
thiamine diphosphate |
wild-type, Hill coefficient 1.38, pH 7.0, 30°C |
759457 |
1.2.1.104 | 0.0016 |
- |
pyruvate |
2-oxoglutarate dehydrogenase complex, pH 7.6, 30°C, in absence of thiamine diphosphate, in presence of 2 mM Ca2+ |
656580 |