EC Number |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference |
---|
1.1.1.23 | -999 |
- |
more |
kinetic isotope effects studies with deuterated histidinols on Salmonella typhimurium HDH reveals that the rate constants obtained at pH 9.0 allow kinetic simulations indicating a thermodynamically unfavorable but relatively fast hydride transfer from histidinol, and an irreversible and slower second hydride transfer from a histidinal derivative |
741455 |
1.1.1.23 | -999 |
- |
more |
pre-steady-state kinetics and Michaelis-Menten steady-state kinetics, solvent kinetic isotope effects and proton inventory, thermodynamics, detailed overview |
741402 |
1.1.1.23 | -999 |
- |
more |
steady-state kinetics |
721426 |
1.1.1.23 | 0.0027 |
- |
L-histidinal |
- |
286325 |
1.1.1.23 | 0.0027 |
- |
L-histidinol |
- |
286324 |
1.1.1.23 | 0.0027 |
- |
NAD+ |
pH 7.2, 25°C, with Ficoll at 100 g/l |
741402 |
1.1.1.23 | 0.0029 |
- |
NAD+ |
pH 7.2, 25°C |
741402 |
1.1.1.23 | 0.0033 |
- |
NAD+ |
pH 7.2, 25°C, with Ficoll at 200 g/l |
741402 |
1.1.1.23 | 0.0037 |
- |
L-histidinal |
H216N mutation |
286325 |
1.1.1.23 | 0.0049 |
- |
L-histidinol |
recombinant enzyme, pH 7.2, 25°C |
721426 |