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EC Number
Inhibitors
Commentary
Structure
6.3.5.5
4-hydroxymercuribenzoate
-
6.3.5.5
6-diazo-5-oxonorleucine
selective inactivation of Gln-dependent activity
6.3.5.5
6-diazo-5-oxonorleucine
-
6.3.5.5
acivicin
selective time-dependent inhibition of L-Gln-dependent activity, L-Gln protects the enzyme from inactivation. Stimulation of NH4+-dependent activity
6.3.5.5
ADP
competitive with MgATP2-
6.3.5.5
Ala
inhibits glutamine hydrolysis and Gln-dependent carbamoyl phosphate synthesis
6.3.5.5
Alkyl hydrazines
inhibits Gln-dependent activity, but not NH4+-dependent activity
6.3.5.5
Arg
arginine-specific carbamoyl-phosphate synthase is repressed, pyrimidine-specific enzyme not
6.3.5.5
arginine
-
6.3.5.5
azaserine
selective inactivation of Gln-dependent activity
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