EC Number   |
Inhibitors |
Structure |
|---|
  6.3.2.18 | 5-hydroxytryptamine |
effective inhibitor, 1 mM inhibits Nalpha-gamma-L-glutamylhistamine synthesis by 92% |
   |
| 6.3.2.18 | 5-methoxytryptamine |
1 mM inhibits synthesis of Nalpha-gamma-L-glutamylhistamine by 87% |
|
| 6.3.2.18 | DL-octopamine |
effective inhibitor, 1 mM inhibits Nalpha-gamma-L-glutamylhistamine synthesis by 91% |
|
| 6.3.2.18 | dopamine |
effective inhibitor, 1 mM inhibits Nalpha-gamma-L-glutamylhistamine synthesis by 84% |
|
| 6.3.2.18 | gamma-aminobutyric acid |
1 mM inhibits synthesis of Nalpha-gamma-L-glutamylhistamine by 13% |
|
| 6.3.2.18 | L-norepinephrine |
1 mM inhibits synthesis of Nalpha-gamma-L-glutamylhistamine by 73% |
|
| 6.3.2.18 | more |
neither L-histidine nor Nalpha-gamma-L-glutamylhistamine itself have any inhibitory effect on Nalpha-gamma-L-glutamylhistamine formation. In addition, the dipeptides carnosine, homocarnosine, and anserine also have little effect on histamine utilization. Taurine, putrescine, L-tyrosine and L-tryptophan display no inhibitory activity |
|
| 6.3.2.18 | N-acetylserotonin |
1 mM inhibits synthesis of Nalpha-gamma-L-glutamylhistamine by 11% |
|
| 6.3.2.18 | noradrenaline |
1 mM inhibits Nalpha-gamma-L-glutamylhistamine synthesis by 73% |
|
| 6.3.2.18 | serotonin |
1 mM inhibits synthesis of Nalpha-gamma-L-glutamylhistamine by 92% |
|
