EC Number |
Inhibitors |
Structure |
---|
5.3.3.14 | 3-decynoyl-N-acetylcysteamine |
covalent modification of ative site residue H70 |
|
5.3.3.14 | 3-decynoyl-N-acetylcysteamine |
strong inhibition of both dehydrase activity of EC 4.2.1.60 and isomerase activity of enzyme |
|
5.3.3.14 | 3-decynoyl-N-acetylcysteamine |
irreversible inactivation of both dehydrase activity of EC 4.2.1.60 and isomerase activity of enzyme, inhibition occurs through isomerization to the allene and subsequent covalent modification of enzyme |
|
5.3.3.14 | 3-dodecynoyl-N-acetylcysteamine |
- |
|
5.3.3.14 | 3-nonynoyl-N-acetylcysteamine |
noncompetitive |
|
5.3.3.14 | 3-octynoyl-N-acetylcysteamine |
24% inhibition at 0.005 mM |
|
5.3.3.14 | 3-undecynoyl-N-acetylcysteamine |
- |
|
5.3.3.14 | more |
not inhibitory: iodoacetic acid, chloroacetic acid, iodoacetamide, N-ethylmaleimide |
|
5.3.3.14 | p-chloromercuribenzoate |
0.5 mM, 35% inhibition |
|