EC Number   |
Inhibitors |
Structure |
|---|
    5.1.1.18 | (thiophen-3-yl)propanedioate |
- |
   |
| 5.1.1.18 | 1,4-dihydronicotinamide mononucleotide |
the NADH precursor exhibits a partial mixed-type inhibition. Docking simulations suggest that all 1,4-dihydronicotinamide derivatives bind at the interdimeric interface, with the ring positioned in an unoccupied site next to the ATP binding site |
|
| 5.1.1.18 | 1-(4-acetamidoanilino)-1-oxopropan-2-yl 3-[(2-chlorophenyl)sulfanyl]propanoate |
- |
|
| 5.1.1.18 | 1-(4-ethoxyanilino)-1-oxopropan-2-yl 3-[(2-chlorophenyl)sulfanyl]propanoate |
- |
|
| 5.1.1.18 | 1-anilino-1-oxopropan-2-yl 3-[(2-chlorophenyl)sulfanyl]propanoate |
- |
|
| 5.1.1.18 | 2,2-dichloromalonate |
as malonate, it binds in a small pocket of the active site |
|
| 5.1.1.18 | 2,2-dichloromalonate |
- |
|
| 5.1.1.18 | 2,2-difluoromalonate |
- |
|
| 5.1.1.18 | 2-(4-acetamidoanilino)-2-oxoethyl 3-(2-fluorophenoxy)propanoate |
- |
|
| 5.1.1.18 | 2-(4-acetamidoanilino)-2-oxoethyl 3-(phenylsulfanyl)propanoate |
- |
|
