EC Number   |
Inhibitors |
Structure |
|---|
   4.2.1.127 | KCl |
high salt concentrations (NaCl, KCl, or MgCl2 at a concentration of 220 mM) inhibit the enzyme activity completely |
   |
| 4.2.1.127 | linalyl amine |
the simultaneous utilization of 10 mM (3S)-linalool and varying concentrations (0.01-10 mM) of linalyl amine in biotransformations results in almost complete inactixadvation (over 98%) of LinD even when the amine concentration is low |
|
| 4.2.1.127 | MgCl2 |
high salt concentrations (NaCl, KCl, or MgCl2 at a concentration of 220 mM) inhibit the enzyme activity completely |
|
| 4.2.1.127 | more |
not inhibited by 10% (v/v) DMSO. EDTA (5 mM) does not affect the enzyme activity |
|
| 4.2.1.127 | more |
detergent-mediated release of the protein from the membrane causes irreversible inhibitory effects on the enzyme activity |
|
| 4.2.1.127 | more |
no inhibition by EDTA |
|
| 4.2.1.127 | more |
dehydratase and isomerase activities of the bifunctional Ldi are only detectable in the presence of a reductant (dithiothreitol) and in the absence of O2 |
|
| 4.2.1.127 | NaCl |
high salt concentrations (NaCl, KCl, or MgCl2 at a concentration of 220 mM) inhibit the enzyme activity completely |
|
| 4.2.1.127 | O2 |
the enzyme requires dithiothreitol as a reducing agent and an oxygen free microenvironment (less than 1% (v/v)) for the dehydration of linalool |
|
| 4.2.1.127 | pyridoxal 5'-phosphate |
1 mM; 35% inhibition |
|
