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EC Number
Inhibitors
Commentary
Structure
4.2.1.114
(S)-homocitrate
complete inhibition at 0.1 mM
4.2.1.114
cis-aconitate
50% inhibition of the hydrolase activity at 0.025 mM
4.2.1.114
cis-homoaconitate/(R)-homocitrate
mixtures of 0.1 mM cis-homoaconitate and 0.05 mM (R)-homocitrate reduce the HACN hydrolyase activity by 50%
4.2.1.114
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no inhibition by citraconate up to 0.2 mM
4.2.1.114
trans-(homo)3aconitate
50% inhibition of the hydrolase activity at 0.4 mM
4.2.1.114
trans-aconitate
50% inhibition of the hydrolase activity at 0.1 mM
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