EC Number |
Inhibitors |
Structure |
---|
4.1.2.8 | 2,3-dihydroxy-3-[(2-hydroxyphenyl)amino] propyl phosphate |
competetive inhibitor |
|
4.1.2.8 | 2-([[4-(trifluoromethoxy)phenyl]sulfonyl]amino) ethyl phosphate |
competetive inhibitor |
|
4.1.2.8 | 3-(1H-indol-3-yl)propyl phosphate |
competetive inhibitor |
|
4.1.2.8 | 3-(2,3-dihydro-1H-indol-3-yl)glycerol phosphate |
competetive inhibitor |
|
4.1.2.8 | 3-acetyl-L-aspartic acid |
inhibits the alpha-reaction. Indole 3-acetylglycine and 3-acetyl-L-aspartic acid are similar to complexes that are similar to 3-(1H-indol-3-yl)propyl phosphate with the phosphoryl sub-site occupied by the ligand carboxylate, the indole ring NH H-bonded to alphaAsp60, and one carboxylate oxygen of the catalytic alphaGlu49 H-bonded to the acetyl oxygen |
|
4.1.2.8 | 4-[(2-aminophenyl)sulfonyl]butyl phosphate |
competetive inhibitor |
|
4.1.2.8 | indole 3-acetylglycine |
inhibits the alpha-reaction. Indole 3-acetylglycine and 3-acetyl-L-aspartic acid are similar to complexes that are similar to 3-(1H-indol-3-yl)propyl phosphate with the phosphoryl sub-site occupied by the ligand carboxylate, the indole ring NH H-bonded to alphaAsp60, and one carboxylate oxygen of the catalytic alphaGlu49 H-bonded to the acetyl oxygen |
|