EC Number   |
Inhibitors |
Structure |
|---|
   3.6.1.59 | C5-substituted quinazolines |
C5-quinazolines potently inhibit DcpS decapping activity. Binding of C5-substituted quinazolines to DcpS holds the enzyme in an open, catalytically incompetent conformation |
 |
| 3.6.1.59 | D156844 |
highly effective at inhibiting recombinant DcpS decapping activity |
  |
| 3.6.1.59 | Dcs2 protein |
Dcs2 is recruited into cytoplasmic P bodies, its inhibitory function may be focused in these centres of mRNA storage/turnover. Dcs2 is a stress-induced regulatory protein that modulates m7GpppX pyrophosphatase activity |
|
| 3.6.1.59 | KCl |
the decapping reaction is significantly inhibited by increasing salt concentration, with KCl being a more potent inhibitor than NaCl |
|
| 3.6.1.59 | m7G5'ppp5'G |
- |
|
| 3.6.1.59 | NaCl |
the decapping reaction is significantly inhibited by increasing salt concentration, with KCl being a more potent inhibitor than NaCl |
|
