EC Number   |
Inhibitors |
Structure |
|---|
   3.5.4.29 | 8-azido-GTP |
0.6 mM, 91% inhibition of GTP cyclohydrolase activity, 0.3 mM, 53% inhibition of diphosphate phosphohydrolase activity |
   |
| 3.5.4.29 | 8-bromo-GTP |
0.1 mM, 50% inhibition of GTP cyclohydrolase activity, 0.1 mM, 64% inhibition of diphosphate phosphohydrolase activity |
|
| 3.5.4.29 | alpha,beta-methylene-GTP |
0.06 mM, 80% inhibition of GTP cyclohydrolase activity, 0.6 mM, 33% inhibition of diphosphate phosphohydrolase activity |
|
| 3.5.4.29 | beta,gamma-methylene-GTP |
0.6 mM, 34% inhibition of GTP cyclohydrolase activity |
|
| 3.5.4.29 | diphosphate |
inhibition of diphosphate phosphohydrolase activity at high concentrations |
|
| 3.5.4.29 | GDP |
more than 40% inhibition of GTP cyclohydrolase activity |
|
| 3.5.4.29 | GMP |
more than 40% inhibition of GTP cyclohydrolase activity |
|
| 3.5.4.29 | GTP-gamma-S |
0.6 mM, 80% inhibition of GTP cyclohydrolase activity |
|
| 3.5.4.29 | IMP |
0.6 mM, 25% inhibition of GTP cyclohydrolase activity |
|
| 3.5.4.29 | methylene diphosphate |
0.6 mM, 40% inhibition of GTP cyclohydrolase activity, 0.6 mM, 56% inhibition of diphosphate phosphohydrolase activity |
|
