EC Number   |
Inhibitors |
Structure |
|---|
    3.5.1.42 | alpha-nicotinic acid adenine dinucleotide |
non-competitive inhibitor, Ki: 8 mM |
   |
| 3.5.1.42 | alpha-nicotinic acid mononucleotide |
non-competitive inhibitor, Ki: 21 mM |
|
| 3.5.1.42 | beta-nicotinic acid adenine dinucleotide |
non-competitive inhibitor, Ki: 7 mM |
|
| 3.5.1.42 | Cu2+ |
strong inhibitor |
|
| 3.5.1.42 | deamido-NAD+ |
product inhibition |
|
| 3.5.1.42 | Hg2+ |
52% inhibition at 1 mM |
|
| 3.5.1.42 | Isonicotinic acid |
non-competitive inhibitor, Ki: 8.3 mM |
|
| 3.5.1.42 | Mg2+ |
- |
|
| 3.5.1.42 | more |
not affected by EDTA up to 10 mM, the enzyme retains its activity in the presence of 0.2 mM iodoacetamide |
|
| 3.5.1.42 | more |
no inhibition by PMSF and desthiobiotin-fluorophosphonate |
|
