EC Number   |
Inhibitors |
Structure |
|---|
   3.4.24.87 | 1,10-phenanthroline |
activity can be restored by Ca2+ |
   |
| 3.4.24.87 | Ca2+ |
enzyme catalytic activity in blood plasma is tuned by varying buffer calcium, with lower divalent ion concentrations enhancing cleavage |
|
| 3.4.24.87 | citrate |
weak |
|
| 3.4.24.87 | Cl- |
Chloride ions inhibit von Willebrand factor hydrolysis by ADAMTS-13 of the A1-A2-A3 and A1-A2 domains in the presence of either urea or high shear stress, whereas this effect is either absent or negligible when using A2 and A2-A3 domains |
|
| 3.4.24.87 | CoCl2 |
an increasing concentration of CoCl2 inhibits ADAMTS13 activity |
|
| 3.4.24.87 | EDTA |
activity can be restored by Ca2+, complete inhibition |
|
| 3.4.24.87 | EDTA |
complete inhibition |
|
| 3.4.24.87 | EDTA |
- |
|
| 3.4.24.87 | EDTA |
complete inhibition at 10 mM |
|
| 3.4.24.87 | EDTA |
no activity in the presence of EDTA |
|
