EC Number |
Inhibitors |
Structure |
---|
3.4.24.60 | (24-28)ANF pentapeptide |
i.e. Asn-Ser-Phe-Arg-Tyr, weak, substance P as substrate, inhibits cleavage of Gly9-Leu10 and Phe7-Phe8 bonds |
|
3.4.24.60 | (25-28)ANF tetrapeptide |
i.e. Ser-Phe-Arg-Tyr, weak, substance P as substrate, inhibits cleavage of Gly9-Leu10 and Phe7-Phe8 bonds |
|
3.4.24.60 | (Leu5)-enkephalin |
inhibitor of dactylysin towards substance P |
|
3.4.24.60 | (Met5)-enkephalin |
inhibitor of dactylysin towards substance P |
|
3.4.24.60 | 1,10-phenanthroline |
metalloendopeptidase character |
|
3.4.24.60 | 1,10-phenanthroline |
0.01 or 0.05 mM Zn2+, Ca2+ or Mn2+ fully restores; metalloendopeptidase character |
|
3.4.24.60 | 1,10-phenanthroline |
strongly inhibits |
|
3.4.24.60 | Acetorphan |
less efficient than phosphoramidon |
|
3.4.24.60 | benzamidine |
weak |
|
3.4.24.60 | benzamidine |
not |
|