EC Number   |
Inhibitors |
Structure |
|---|
    3.4.13.22 | ([(1-aminoethyl)(hydroxy)phosphoryl]oxy)acetic acid |
phosphonate dipeptide analogs of D-Ala-D-Ala |
   |
| 3.4.13.22 | 2-([(1-aminoethyl) (hydroxy) phosphoryl]oxy)propanoic acid |
phosphonate dipeptide analogs of D-Ala-D-Ala |
|
| 3.4.13.22 | Cu2+ |
96% inhibition at 1 mM |
|
| 3.4.13.22 | Cu2+ |
- |
|
| 3.4.13.22 | D-3-[(1-aminoethyl)phosphinyl]-D-2-methylpropionic acid |
phosphinate analogue of the proposed tetrahedral intermediate of the hydrolysis reaction, slow binding |
|
| 3.4.13.22 | D-3-[(1-aminoethyl)phosphinyl]-D-2-methylpropionic acid |
phosphinate analogue of the proposed tetrahedral intermediate of the hydrolysis reaction |
|
| 3.4.13.22 | D-3-[(1-aminoethyl)phosphonyl]-D-2-methylpropionic acid |
phosphonate analogue of the proposed tetrahedral intermediate of the hydrolysis reaction |
|
| 3.4.13.22 | D-Ala-D-(2-difluorothio)glycine-OH |
dipeptide-like mechanism-based inhibitor, cleavage of the substance results in formation of a highly reactive 4-thioquinone fluoromethide which covalently reacts with the enzyme resulting in irreversible inhibition, inhibition mechanism |
|
| 3.4.13.22 | D-Ala-D-Ala |
competitive substrate |
|
| 3.4.13.22 | D-Ala-D-lactate |
very poor hydrolysis, blocking of the enzyme |
|
