EC Number |
Inhibitors |
Structure |
---|
3.4.11.7 | (1-aminopropane-1,3-diyl)bis(phosphonic acid) |
- |
|
3.4.11.7 | (3R)-3-amino-3-phosphonopropanoic acid |
- |
|
3.4.11.7 | (4R)-4-amino-5-sulfanylpentanoic acid |
a linear competitive inhibitor |
|
3.4.11.7 | (R)-3-amino-4-mercaptobutane-1-sulfonic acid |
i.e. EC33 |
|
3.4.11.7 | (S)-3-amino-4-mercapto-butyl sulfonic acid |
i.e. EC33 |
|
3.4.11.7 | (S)-3-amino-4-mercapto-butyl sulfonic acid |
i.e. EC33, a selective APA inhibitor, docking analysis in the presence of Ca2+, the ligand interacts with S1 subsite of Arg-878 in murine APA, three-dimensional structure modelling reavealing a change in the volume of the S1 subsite, which may impair the binding and/or the optimal positioning of the substrate in the active site as well as its hydrolysis, overview |
|
3.4.11.7 | (S)-3-amino-4-mercapto-butylsulfonic acid |
specific and selective aminopeptidase A inhibitor |
|
3.4.11.7 | (S)-3-amino-4-mercapto-butylsulfonic acid |
specific and selective APA inhibitor |
|
3.4.11.7 | (S)-3-amino-4-mercaptobutyl sulfonic acid |
EC33, specific and selective APA inhibitor |
|
3.4.11.7 | 1,10-phenanthroline |
reactivation by Co2+ or Zn2+ |
|