EC Number   |
Inhibitors |
Structure |
|---|
   3.2.1.147 | (2-sulfato)ethyl 1-thio-beta-D-glucopyranoside |
10mM, 30% inhibition |
   |
| 3.2.1.147 | (2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine |
inhibition of hydrolysis of sinigrin and progoitrin at pH 5 and at pH 7 |
|
| 3.2.1.147 | (2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine |
- |
|
| 3.2.1.147 | (3-sulfato)propyl 1-thio-beta -D-glucopyranoside |
IC50: 5 mM |
|
| 3.2.1.147 | (3-sulfonato)propyl 1-thio-beta-D-glucopyranoside |
10 mM, 15% inhibition |
|
| 3.2.1.147 | (Z)-(1-((2-(dimethylammonio)ethyl)thio)-2-phenylethylidene)amino sulfate |
a competitive inhibitor. The sulfate group and the phenyl group of the inhibitor bind to the aglycon-binding site of the enzyme, whereas the N,N-dimethyl group binds to the glucose-binding site, binding structure, overview |
|
| 3.2.1.147 | 1,10-phenanthroline |
- |
|
| 3.2.1.147 | 1,10-phenanthroline |
1 mM, 26% inhibition |
|
| 3.2.1.147 | 1,4-dideoxy-1,4-imino-D-arabinitol |
inhibition of hydrolysis of progoitrin at pH 5 in citrate buffer and at pH 7 in phosphate buffer, inhibition of hydrolysis of sinigrin at pH 7 in phosphate buffer, no hydrolysis of progoitrin and sinigrin at pH 5 in acetate buffer |
|
| 3.2.1.147 | 1-deoxynojirimycin |
inhibition of hydrolysis of progoitrin at pH 5 in citrate buffer and at pH 7 in phosphate buffer, inhibition of hydrolysis of sinigrin at pH 7 in phosphate buffer, no hydrolysis of progoitrin and sinigrin at pH 5 in acetate buffer |
|
