EC Number |
Inhibitors |
Structure |
---|
3.2.1.108 | 2-fluoro-dinitrophenylglucoside |
specifically inhibits phlorizin hydrolase, lactase activity is inhibited slowly |
|
3.2.1.108 | cerebroside |
bovine brain cerebroside |
|
3.2.1.108 | D-glucal |
40% inhibition for 4-O-beta-D-galactopyranosyl-D-xylose and 75% inhibition for 3-O-beta-D-galactopyranosyl-D-xylose at 100 mM D-glucal, no increase of inhibition above 100 mM D-glucal |
|
3.2.1.108 | epigallocatechin-3-gallate |
inhibition by epigallocatechin-3-gallate of lactase is alleviated about 1.7fold by proline-rich proteins |
|
3.2.1.108 | gluconolactone |
- |
|
3.2.1.108 | more |
rotavirus impairs lactase enzymatic activity by an NSP4-dependant mechanism in brush border of human enterocyte-like Caco-2 cells, the infected brush border membranes show an enzyme with altered kinetics, overview |
|
3.2.1.108 | N-(n-butyl)-deoxygalactojirimycin |
- |
|
3.2.1.108 | NSP4 |
impairment of lactase activity observed during rotavirus infection results from an inhibitory action of the secreted non-structural rotavirus protein NSP4 |
|
3.2.1.108 | phlorizin |
- |
|
3.2.1.108 | phlorizin |
competitive inhibitor of lactose hydrolysis |
|