EC Number   |
Inhibitors |
Structure |
|---|
   3.1.1.29 | 3'-deoxy-N[(O-methyl-L-tyrosyl)amino]adenosine |
- |
   |
| 3.1.1.29 | 3'-L-(N,N-diacetyl-lysinyl)amino-3'-deoxyadenosine |
- |
|
| 3.1.1.29 | 5-azacytidine |
- |
|
| 3.1.1.29 | 70 S ribosome |
free N-carbobenzyloxy-Phe-tRNA is rapidly cleaved by the enzyme. When bound to a 30 S ribosome in the presence of poly(U), the substrate is hydrolyzed rapidly as when free. The addition of 50 S ribosomal subunits to form the 70S ribosomal binding complex protects the bound substrate from the enzyme |
|
| 3.1.1.29 | deacetylated tRNA |
- |
|
| 3.1.1.29 | diethyldicarbonate |
0.5 mM, 90% inactivation after 10 min, activity can be recovered to 41% of initial activity by treatment wit 200 mM hydroxylamine |
|
| 3.1.1.29 | EDTA |
0.01 mM |
|
| 3.1.1.29 | EDTA |
5 mM, complete inhibition |
|
| 3.1.1.29 | Mg2+ |
0.1 mM |
|
| 3.1.1.29 | more |
cytarabine-enzyme binding and enzyme immobilization analysis using tryptophan fluorescence and surface plasmon resonance, binding complex structure analysis, overview. Strong binding affinity of cytarabine with Pth. This compound successfully kills bacteria in both sensitive and in resistant isolates of bacteria, antibacterial potential of cytrabine is determined by agar diffusion assay |
|
