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Results 1 - 10 of 17 > >>
EC Number Inhibitors Commentary Structure
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35CPZEN-45 a caprazamycin derivative, CPZEN-45 shows excellent antitubercular activity against not only drug-sensitive strains but also some multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis strains Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35DMSO 50% inhibition at 10% v/v, no inhibition at 2.86% v/v Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35more synthesis and evaluation of a series of capuramycin analogues as WecA enzyme inhibitors. No inhibition by capuramycin, UT-01309, and SQ641 Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35more poor inhibition by caprazamycin B Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35Rifampin the sensitivity of wild-type mc2155 strain against rifampin is enhanced in the presence of low concentrations of tunicamycin, a natural WecA inhibitor. An enzyme knockdown mutant strain also shows increased sensitivity to rifampin Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35tunicamycin complete inhibition at 0.02 mg/ml, 36% at 20 ng/ml Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35tunicamycin - Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35UT-01320 complete inhibition at 0.02 mg/ml, 42% at 20 ng/ml Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35UT-01320 a selective WecA inhibitor that kills both replicating and non-replicating Mycobacterium tuberculosis cells at 0.0015-0.00258 mg/ml , respectively Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.35UT-01320 - Go to the Ligand Summary Page
Results 1 - 10 of 17 > >>