2.7.8.15 | aminouridyl phenoxypiperidinbenzyl butanamide |
APPB, APPB shows a strong DPAGT1 inhibitory activity and selectively inhibits growth of the solid tumors at low micromolar concentrations, but does not inhibit growth of a leukemia cell and the healthy cells at these concentrations. Growth inhibition of APPB against the solid cancers is correlated with the expression level of DPAGT1. Docking studies of APPB to DPAGT1, overview |
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