EC Number |
Inhibitors |
Structure |
---|
2.7.7.85 | 3'-dATP |
competitive inhibitor of the diadenylate cyclase domain, binds in the same position as ATP |
|
2.7.7.85 | 3'-deoxyATP |
cordycepin triphosphate |
|
2.7.7.85 | 3'-deoxyATP |
cordycepin triphosphate; cordycepin triphosphate |
|
2.7.7.85 | CdaR |
the extracytoplasmic regulator CdaR interacts with CdaA via its transmembrane helix to modulate c-di-AMP production |
|
2.7.7.85 | competence-stimulating peptide |
CSP, reduces the growth of the wild-type strain by 9% and the growth of the cdaA* V76G mutant strain by 94% compared to without CSP |
|
2.7.7.85 | cordycepin |
3'-deoxy adenosine |
|
2.7.7.85 | cordycepin |
3'-deoxy adenosine; 3'-deoxy adenosine |
|
2.7.7.85 | GlmM |
binds directly to enzyme CdaA in the CdaA-CdaR-GlmM protein complex |
|
2.7.7.85 | GlmM |
binds directly to enzyme CdaA in the CdaA-CdaR-GlmM protein complex; binds directly to enzyme CdaA in the CdaA-CdaR-GlmM protein complex |
|
2.7.7.85 | GlmM |
a soluble phosphoglucosamine mutase, GlmM forms a complex with CdaA and inhibits the diadenylate cyclase activity in vitro. GlmM inhibits c-di-AMP production in Listeria monocytogenes when the bacteria encounter osmotic stress |
|