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EC Number
Inhibitors
Commentary
Structure
2.7.2.11
3,4-dehydro-L-proline
9% residual activity at 1 mM
2.7.2.11
5-oxo-L-Pro
12 mM, 10% inhibition
2.7.2.11
5-oxoproline
AAK domain has a crater on the beta sheet C-edge that hosts the active centre and binds 5-oxoproline
2.7.2.11
ADP
-
2.7.2.11
alpha-methyl-L-proline
82% residual activity at 1 mM
2.7.2.11
As2+
applied into soil strongly decreases activity by 87.7%
2.7.2.11
Cd2+
0.1 mM, complete inhibition
2.7.2.11
Cd2+
applied into soil strongly decreases activity
2.7.2.11
Cd2+
increased content in soil decreases enzyme activity
2.7.2.11
cis-4-hydroxy-L-proline
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