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Results 1 - 10 of 309 > >>
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EC Number Inhibitors Commentary Structure
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2E)-3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]prop-2-enoic acid CJ-15,801, an enamide analogue of pantothenate isolated from the fungus Seimatosporium sp. CL28611. CJ-15,801 is phosphorylated by pantothenate kinase (PanK). Subsequently, phospho-CJ-15,801 is accepted as a substrate by the next enzyme in the pathway (phosphopantothenoylcysteine synthetase, PPCS), and reacts to become cytidylylated. The cytidylylated phospho-CJ-15,801, which closely mimics the natural reaction intermediate and binds tightly and reversibly to the enzyme, does not react further and instead inhibits the enzyme Go to the Ligand Summary Page
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2E)-3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]prop-2-enoic acid - Go to the Ligand Summary Page
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2E)-3-[[(2S)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]prop-2-enoic acid - Go to the Ligand Summary Page
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2R)-2,4-dihydroxy-3,3-dimethyl-N'-phenylbutanohydrazide competitive, pantothenic acid analogue with 2,4-dihydroxy-3,3-dimethylbutyramide core of pantothenate, inhibition mechanism Go to the Ligand Summary Page
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2R)-2,4-dihydroxy-3,3-dimethylbutanohydrazide competitive, pantothenic acid analogue with 2,4-dihydroxy-3,3-dimethylbutyramide core of pantothenate, inhibition mechanism Go to the Ligand Summary Page
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2R)-2,4-dihydroxy-N-(2-hydroxyethyl)-3,3-dimethylbutanamide competitive, pantothenic acid analogue with 2,4-dihydroxy-3,3-dimethylbutyramide core of pantothenate, inhibition mechanism Go to the Ligand Summary Page
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2R)-N-(2,3-dihydroxypropyl)-2,4-dihydroxy-3,3-dimethylbutanamide competitive, pantothenic acid analogue with 2,4-dihydroxy-3,3-dimethylbutyramide core of pantothenate, inhibition mechanism Go to the Ligand Summary Page
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2R)-N-allyl-2,4-dihydroxy-3,3-dimethylbutanamide competitive, pantothenic acid analogue with 2,4-dihydroxy-3,3-dimethylbutyramide core of pantothenate, inhibition mechanism Go to the Ligand Summary Page
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2Z)-3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]prop-2-enoic acid - Go to the Ligand Summary Page
Show all pathways known for 2.7.1.33Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.33(2Z)-3-[[(2S)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]prop-2-enoic acid - Go to the Ligand Summary Page
Results 1 - 10 of 309 > >>
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