EC Number |
Inhibitors |
Structure |
---|
2.5.1.20 | (Z)-2-farnesyl-3-methylbutenedioic acid dilithium salt |
i.e. SG-129, 25% inhibition at 0.18 mM, noncompetitive |
|
2.5.1.20 | (Z)-2-farnesyl-3-methylbutenedioic acid dilithium salt |
i.e. SG-129, 27-48% inhibition at 0.18 mM, competitive |
|
2.5.1.20 | (Z)-2-octyl-3-methylbutenedioic acid dilithium salt |
i.e. SG-296, 40% inhibition at 0.18 mM |
|
2.5.1.20 | alpha-hydroxyfarnesylphosphonic acid |
i.e. HFPA, competitive |
|
2.5.1.20 | chaetomellic acid |
inhibitory in 20fold molar excess over isopentenyl diphosphate or 200fold molar excess over farnesyl diphosphate, competitive |
|
2.5.1.20 | chaetomellic acid |
27-48% inhibition at 0.18 mM, competitive |
|
2.5.1.20 | Co2+ |
0.1-1 mM, complete inhibition |
|
2.5.1.20 | diphosphate |
- |
|
2.5.1.20 | EDTA |
50 mM, strong inhibition |
|
2.5.1.20 | EDTA |
4 mM, no residual activity |
|