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EC Number
Inhibitors
Commentary
Structure
2.4.1.212
2-deoxyglucose
-
2.4.1.212
4-methylesculetin
-
2.4.1.212
4-Methylumbelliferone
changes the localization of the enzyme by preventing its association with the plasma membrane
2.4.1.212
4-Methylumbelliferone
-
2.4.1.212
4-Methylumbelliferone
inhibits HAS because it depletes UDPGlcUA in cells; inhibits HAS because it depletes UDPGlcUA in cells; inhibits HAS because it depletes UDPGlcUA in cells
2.4.1.212
5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside
modulates aortic smooth muscle cell motility and adhesive properties through AMP-activated protein kinase, AMPK
2.4.1.212
AG825
ErbB2 inhibitor, blocks the heregulin-mediated HAS isozyme phosphorylation/activation; ErbB2 inhibitor, blocks the heregulin-mediated HAS isozyme phosphorylation/activation; ErbB2 inhibitor, blocks the heregulin-mediated HAS isozyme phosphorylation/activation
2.4.1.212
brefeldin A
-
2.4.1.212
ceramide
-
2.4.1.212
DTNB
52% inhibition at 0.5 mM
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