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Results 1 - 10 of 23 > >>
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EC Number Inhibitors Commentary Structure
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1331,4-diamino-2,3-dicyano-1,4-bis-(2-aminophenylthio)butadiene 0-10 microM of specific inhibitor U0126 of MAP kinase cascade inhibits beta-1,4-GalT I mRNA production induced by lipopolysaccharide Go to the Ligand Summary Page
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1332-(6-hydroxynaphthyl) beta-D-xylopyranoside - Go to the Ligand Summary Page
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1333-acetamido-propyl beta-D-xylopyranoside - Go to the Ligand Summary Page
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1333-benzamido-propyl beta-D-xylopyranoside - Go to the Ligand Summary Page
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1333-hexanamido-propyl beta-D-xylopyranoside - Go to the Ligand Summary Page
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1334-methylumbelliferyl 4-deoxy-beta-D-fluoroxylose - Go to the Ligand Summary Page
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1334-methylumbelliferyl 4-deoxy-beta-D-xylopyranoside - Go to the Ligand Summary Page
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1334-methylumbelliferyl 4-deoxy-beta-D-xyloside - Go to the Ligand Summary Page
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1334-methylumbelliferyl 4-fluoro-beta-D-xylopyranoside 50% inhibition at 2 mM. The strategic position of Tyr194 forming stacking interactions with the aglycone, and the hydrogen bond between the His195 nitrogen backbone and the carbonyl group of the coumarinyl molecule to develop a tight binder of the enzyme. This leads to the synthesis of 4-deoxy-4-fluoroxylose linked to 4-methylumbelliferone that inhibits enzyme activity in vitro with a Ki 10 times lower than the Km value and efficiently impairs glycosaminoglycan synthesis in a cell assay Go to the Ligand Summary Page
Show all pathways known for 2.4.1.133Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.1334-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl] phenol 10-30 microM of specific inhibitor SB202190 of MAP kinase cascade inhibits beta-1,4-GalT I mRNA production induced by lipopolysaccharide Go to the Ligand Summary Page
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