EC Number   |
Inhibitors |
Structure |
|---|
  2.3.1.172 | acetyl-CoA |
1 mM, 48% inhibition |
   |
| 2.3.1.172 | caffeic acid |
10 mM, complete inhibition |
|
| 2.3.1.172 | CoA-SH |
product inhibition, competitive versus malonyl-CoA, noncompetitive versus shisonin |
|
| 2.3.1.172 | Cu2+ |
0.1 mM, complete inhibition |
|
| 2.3.1.172 | diethyldicarbonate |
1 mM, 51% inhibition, 20 min, 20°C |
|
| 2.3.1.172 | Hg2+ |
0.1 mM, complete inhibition |
|
| 2.3.1.172 | malonylshisonin |
product inhibition, noncompetitive versus shisonin and malonyl-CoA |
|
| 2.3.1.172 | more |
not inhibited by Ca2+, Cd2+, Co2+, Fe2+, Mg2+, Mn2+, Ni2+, Sn2+, Zn2+, all at 0.1 mM, 1 mM dithiothreitol, 1 mM EDTA, 1% Tween 20, 1% Triton X-100, 0.1% CHAPS, 0.1 mM pelargonidin 3,5-diglucoside, 10 mM glucose |
|
| 2.3.1.172 | N-ethylmaleimide |
5 mM, 53% inhibition, 20 min, 20°C |
|
| 2.3.1.172 | p-coumaric acid |
dead-end inhibitor, competitive with respect to shisonin, uncompetitive with respect to malonyl-CoA |
|
