EC Number |
Inhibitors |
Structure |
---|
1.4.1.4 | 2,4-pyridinedicarboxylate |
- |
|
1.4.1.4 | 2,4-pyridinedicarboxylate |
inhibits less efficiently |
|
1.4.1.4 | 2,4-pyridinedicarboxylate |
weak inhibitor |
|
1.4.1.4 | 2-hydroxyethyl disulfide |
attenuation of reductive amination (forward) activity but a negligible effect on oxidative deamination (reverse) activity |
|
1.4.1.4 | 2-Methyleneglutarate |
- |
|
1.4.1.4 | 2-Methyleneglutarate |
weak inhibitor |
|
1.4.1.4 | 2-oxoglutarate |
competitive inhibitor of the deamination |
|
1.4.1.4 | 2-oxoglutarate |
shows allosteric properties and a sigmoid response (nH=2.5) towards 2-oxoglutarate saturation |
|
1.4.1.4 | 2-oxoglutarate |
substrate inhibition above 2.0 mM |
|
1.4.1.4 | 4-chloromercuribenzoate |
at 1 mM, 86% inhibition |
|