EC Number |
Inhibitors |
Structure |
---|
1.14.16.4 | (2S)-2-amino-5-(2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl)pent-4-ynoic acid |
- |
|
1.14.16.4 | (3R)-8-(2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid |
- |
|
1.14.16.4 | (3S)-8-(2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid |
- |
|
1.14.16.4 | (3S)-8-(2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl)-2-methyl-2,8-diazaspiro[4.5]decane-3-carboxylic acid |
- |
|
1.14.16.4 | (6R)-5,6,7,8-tetrahydrobiopterin |
- |
|
1.14.16.4 | (6R)-L-erytho-5,6,7,8-tetrahydrobiopterin |
TPH2, substrate inhibition |
|
1.14.16.4 | (7R)-5,6,7,8-tetrahydrobiopterin |
recombinant pinal enzyme, 2.1 mM, 50% inhibition |
|
1.14.16.4 | 1,10-phenanthroline |
- |
|
1.14.16.4 | 1,10-phenanthroline |
0.0024 mM, 50% inhibition, competitive vs. tryptophan |
|
1.14.16.4 | 2,2'-dipyridyl |
- |
|