EC Number |
Inhibitors |
Structure |
---|
1.14.16.1 | (6R)-L-erythro-tetrahydrobiopterin |
inhibits phenylalanine and lysolecithin activation |
|
1.14.16.1 | (6R)-L-erythro-tetrahydrobiopterin |
modulator that inhibits activation |
|
1.14.16.1 | (7R)-5,6,7,8-tetrahydrobiopterin |
- |
|
1.14.16.1 | (7R)-5,6,7,8-tetrahydropterin |
0.001 mM, 50% inhibition at 0.5 mM phenylalanine, 0.004 mM, 50% inhibition at 0.1 mM phenylalanine, recombinant enzyme |
|
1.14.16.1 | (7R)-tetrahydrobiopterin |
slight inhibition, synthetic pathway, overview, conformational structure by NMR |
|
1.14.16.1 | (7S)-tetrahydrobiopterin |
strong, competitive inhibition, synthetic pathway, overview, conformational structure by NMR |
|
1.14.16.1 | 2,2'-dipyridine |
- |
|
1.14.16.1 | 2,2'-dipyridyl |
99.0% inhibition at 1.0 mM using L-phenylalanine as substrate, 99.0% inhibition at 1.0 mM using S-carboxymethyl-L-cysteine as substrate |
|
1.14.16.1 | 2,3-dihydroxynaphthalene |
binds to Fe3+ on enzyme that is oxidized during catalysis |
|
1.14.16.1 | 2-mercaptoethanol |
2 mM, 80% inhibition |
|