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Results 1 - 4 of 4
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EC Number Inhibitors Commentary Structure
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.68GSK-J4 both the mRNA and protein levels of mPR3 are significantly reduced compared to controls Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.68GSK-J4 specific inhibitor, application dramatically suppresses Th17 cell differentiation in vitro Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.68GSK-J4 specific inhibitor of the H3K27me3 histone demethylases UTX and JMJD3, inhibits herpes simplex virus HSV-1 reactivation from sensory neurons in vitro; specific inhibitor of the H3K27me3 histone demethylases UTX and JMJD3, inhibits herpes simplex virus HSV-1 reactivation from sensory neurons in vitro Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.68GSKJ4 inhibitor is active against native and temozolomide-resistant glioblastoma cells, albeit at at a lower effcacy than JIB 04, inhibitor of lysine demethylase KDM5A, EC 1.14.11.67. GSK J4 and JIB 04 strongly synergize and are a potent combination against temozolomide-resistant glioblastoma cells. GSK J4 does not synergize with temozolomide Go to the Ligand Summary Page
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