EC Number |
Inhibitors |
Structure |
---|
1.14.11.57 | 2-oxoglutarate |
inhibitory above 0.5 mM |
|
1.14.11.57 | 3,4-dihydroxybenzoate |
- |
|
1.14.11.57 | Co2+ |
0.5 mM, complete inhibition |
|
1.14.11.57 | diethyl dicarbonate |
complete inhibition. Inactivation can be partially prevented by the inclusion of L-proline and 2-oxoglutarate in the preincubation mixture |
|
1.14.11.57 | L-ascorbate |
ascorbate causes a time-dependent inhibition of L-proline hydroxylation. The addition of ascorbate does not stimulate L-proline-coupled turnover of 2-oxoglutarate, but does stimulate L-proline-uncoupled turnover |
|
1.14.11.57 | Pyridine-2,4-dicarboxylate |
competitive with respect to 2-oxoglutarate |
|
1.14.11.57 | Pyridine-2,5-dicarboxylate |
- |
|
1.14.11.57 | Zn2+ |
0.5 mM, complete inhibition |
|