EC Number   |
Inhibitors |
Structure |
|---|
   1.11.1.24 | ADP |
inhibitory at 2 mM |
   |
| 1.11.1.24 | AMP |
inhibitory at 2 mM |
|
| 1.11.1.24 | ATP |
3 mM ATP in concert with Mg2+, Ca2+, Mn2+, or Zn2+ lowers the peroxidase activity in a dose-dependent manner |
|
| 1.11.1.24 | Ca2+ |
92% inhibition at 2 mM, in the presence of 3 mM ATP |
|
| 1.11.1.24 | H2O2 |
- |
|
| 1.11.1.24 | H2O2 |
highly susceptible to inactivation by H2O2; highly susceptible to inactivation by H2O2 |
|
| 1.11.1.24 | H2O2 |
significant reductions in Prx II is detected at H2O2 concentrations above 0.6 mM; significant reductions in Prx I is detected at H2O2 concentrations above 0.6 mM |
|
| 1.11.1.24 | H2O2 |
high concentrations of H2O2 temporarily inactivate Tpx1 |
|
| 1.11.1.24 | H2O2 |
excess of H2O2 inactivates the enzyme by overoxidation |
|
| 1.11.1.24 | H2O2 |
1 mM H2O2 overoxidizes isoform Prx2 at the peroxidatic cysteine and results in the loss of the peroxidase activity |
|
