EC Number |
Inhibitors |
Structure |
---|
1.1.1.64 | (+)-gossypol |
- |
|
1.1.1.64 | (-)-gossypol |
- |
|
1.1.1.64 | (2,4-dihydroxyphenyl)-phenylmethanone |
- |
|
1.1.1.64 | (2E)-3-(4-bromophenyl)-2-[4-(methylsulfonyl)phenyl]prop-2-enoic acid |
93.3% inhibition at 0.1 mM |
|
1.1.1.64 | (2E)-3-(4-ethylphenyl)-2-[4-(methylsulfonyl)phenyl]prop-2-enoic acid |
89.1% inhibition at 0.1 mM |
|
1.1.1.64 | (2E)-3-(4-methylphenyl)-2-[4-(methylsulfonyl)phenyl]prop-2-enoic acid |
92.7% inhibition at 0.1 mM |
|
1.1.1.64 | (2E)-3-[4-(methylsulfanyl)phenyl]-2-[4-(methylsulfonyl)phenyl]prop-2-enoic acid |
93.5% inhibition at 0.1 mM |
|
1.1.1.64 | (3,6-dihydropyridin-1(2H)-yl)(1H-indol-2-yl)methanone |
crystal structure analysis of enzyme-inhibitor complex |
|
1.1.1.64 | (3alpha,5alpha)-3-([(2R,5S)-2,5-dimethyl-4-[2-(trifluoromethyl)benzene-1-sulfonyl]piperazin-1-yl]methyl)-3-hydroxyandrostan-17-one |
48.8-92.0% inhibition at 0.0001-0.001 mM |
|
1.1.1.64 | (3alpha,5alpha)-3-([(2R,5S)-2,5-dimethyl-4-[2-(trifluoromethyl)benzene-1-sulfonyl]piperazin-1-yl]methyl)-3-hydroxyandrostan-17-one |
- |
|