EC Number |
Inhibitors |
Structure |
---|
1.1.1.10 | 2-mercaptoethanol |
92% inhibition at 5 mM |
|
1.1.1.10 | 3-hydroxybutyric acid |
50% inhibition at 1.1 mM |
|
1.1.1.10 | 3-hydroxybutyric acid |
50% inhibition at 1.0 mM |
|
1.1.1.10 | 3-hydroxybutyric acid |
50% inhibition at 2.0 mM |
|
1.1.1.10 | 4-methyl-[1,2,3]-thiadiazole-5-carboxylic acid benzyloxyamide |
- |
|
1.1.1.10 | 4-methyl-[1,2,3]-thiadiazole-5-carboxylic acid benzyloxyamide |
IC50: 0.00023 mM for wild-type enzyme, 0.0019 mM for mutant enzyme L143F, 0.0018 mM for mutant enzyme H146L, 0.0029 mM for mutant enzyme W191S, 0.00079 mM for mutant enzyme W191F |
|
1.1.1.10 | 4-methylthiophene-2-carboxylic acid N'-(2,3,3-trichloroacryloyl)-hydrazide |
IC50: 0.0003 mM for wild-type enzyme, 0.00056 mM for mutant enzyme L143F, 0.002 mM for mutant enzyme H146L, 0.0002 mM for mutant enzyme W191S, 0.0022 mM for mutant enzyme W191F |
|
1.1.1.10 | acetoacetic acid |
50% inhibition at 0.63 mM |
|
1.1.1.10 | acetoacetic acid |
50% inhibition at 1.8 mM |
|
1.1.1.10 | acetoacetic acid |
50% inhibition at 2.5 mM |
|