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EC Number
Inhibitors
Commentary
Structure
4.3.2.2
more
dithiothreitol increases inhibition of trans-4-hydroxy-2-nonenal; hydroxylamine reverses inhibition of trans-4-hydroxy-2-nonenal
4.3.2.2
more
as hydrophobic interactions are weakened at 8°C and 4°C, the catalytic activity of ASL decreases strikingly and the enzyme dissociates to a mixture of monomer-dimer-trimer, with small amounts of tetramer
4.3.2.2
ATP
weak, competitive
4.3.2.2
Mg2+
concentration of Mg2+ approaching that of EDTA
4.3.2.2
ADP
weak, competitive
4.3.2.2
phosphate
competitive
4.3.2.2
EDTA
above 15 mM
4.3.2.2
AMP
competitive
4.3.2.2
AMP
-
4.3.2.2
AMP
product inhibition competitive versus succinyladenosine monophosphate
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