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Results 1 - 10 of 16 > >>
EC Number
Inhibitors
Commentary
Structure
Br-
-
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Cl-
enhancement of tubulin polymerization by Cl--induced blockade of intrinsic GTPase. GTPase activity of tubulin is lower (2/3-fold) in Cl--containing solutions than that in Cl--free solutions containing Br- or NO3-
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curcumin
-
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diethyldicarbonate
inhibits GTP hydrolysis, but not the assembly reaction
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EDTA
strong inhibition at 2 mM
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GDP
-
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GTP
inhibitory effect produced at concentrations above 3 mM, above 5 mM leads to depolymerization of microtubules
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guanosine 5'-(gamma-fluorotriphosphate)
reversible competitive dead-end inhibitor
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guanosine 5'-(gamma-thiotriphosphate)
inhibits both tubulin polymerization and GTP hydrolysis
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more
the phosphorylated protein shows hardly any activity
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Results 1 - 10 of 16 > >>