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EC Number
Inhibitors
Commentary
Structure
3.4.21.108
5-[5-(2-nitrophenyl)furfuryliodine]1,3-diphenyl-2-thiobarbituric acid
UCF-101
3.4.21.108
antisense HtrA2
significantly inhibits IFN/all-trans retinoic acid-induced degradation of X-linked inhibitor of apoptosis protein
3.4.21.108
CDR1 peptide
ASGYTFTNYGLSWVR
3.4.21.108
diisopropylfluorophosphate
complete inhibition at 4 mM
3.4.21.108
DPMFKL
peptide DPMFKL which inhibits protease HtrA1,
EC 3.4.21.107
, is not inhibitory to enzyme HtrA2 up to 0.1 mM. For protease HtrA2 mutant lacking the regulatory domain, the peptide acts as a competitive inhibitor, displaying a IC50 value of 0.33 mM
3.4.21.108
DSRIWWV
-
3.4.21.108
etoposide
ratio of C161M/APP decreases 66% during 0.0040 mM etoposide-induced apoptosis compared with the non-apoptotic condition
3.4.21.108
FGRWV
-
3.4.21.108
HtrA2 siRNA
-
3.4.21.108
more
ucf-101 fails to exert any additional protective effect in transfected cells
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