EC Number |
Inhibitors |
Structure |
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2.7.4.9 | more |
several different TMP analogues tested and found to be inhibitory |
|
2.7.4.9 | more |
3-azido-3-deoxythymidine monophosphate is not inhibitory, various thymine derivatives tested and found to inhibit activity to different extents |
|
2.7.4.9 | more |
3'-(aminomethyl)-3'-deoxy-2'-fluorothymidine is not inhibitory at 1 mM; 3-azido-3-deoxythymidine monophosphate is not inhibitory, various thymine derivatives tested and found to inhibit activity to different extents |
|
2.7.4.9 | more |
acyclic nucleoside analogues (Z)-2-(4-(thymin-1-yl)but-2-enyl)-1H-benzo[d,e]isoquinoline-1,3(2H)-dione and (Z)-2-(4-(thymin-1-yl)but-2-enyl)-2,3-dihydro-1H-benzo-[d,e]isoquinolin-1-one are not inhibitory up to 0.02 mM |
|
2.7.4.9 | more |
not inhibitory: 2-mercaptoethanol up to 5 mM, AMP, CMP, dCMP, GMP and dGMP and |
|
2.7.4.9 | more |
not inhibited by N-(5'-deoxy-4-thio-alpha-D-thymidin-5'-yl)-N'-phenylthiourea |
|
2.7.4.9 | more |
not inhibited by 3-((2R,3S,5R)-3-hydroxy-5-(5-(hydroxymethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)propanenitrile and 1-((2R,4S,5R)-5-(2-(1H-tetrazol-5-yl)ethyl)-4-hydroxytetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione |
|
2.7.4.9 | ATP |
- |
|
2.7.4.9 | Mn2+ |
slight inhibition |
|
2.7.4.9 | ADP |
100 nM, 64% inhibition |
|