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EC Number
Inhibitors
Commentary
Structure
2.7.11.30
more
a dominant negative SEK1 mutant abolishes the ALK7-induced apoptosis
2.7.11.30
more
ALK1 mediates inhibition of the ALK5/Smad2/3 pathway
2.7.11.30
more
no inhibition of GDF-9-induced receptor activation by Smad6
2.7.11.30
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LY294002 completely abolishes the ALK7 mutant T194D/Smad3-induced synergistic effect by inhibiting interaction between the Smad3-Linker and PDX-1
2.7.11.30
more
inhibitory potency of 5-(pyridin-2-yl)thiazole inhibitors, overview
2.7.11.30
SB203580
-
2.7.11.30
PD98059
-
2.7.11.30
Rapamycin
-
2.7.11.30
LY364947
competitive to ATP, noncompetitive to the peptide substrate, IC50 is 175 nM, mechanism
2.7.11.30
LY364947
IC50 is 51 nM
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