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EC Number
Inhibitors
Commentary
Structure
2.4.2.17
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carbonylcyanide m-chlorophenylhydrazone, which is a potent inhibitor of several enzymes with adenine-containing substrates or coenzymes has no effect
2.4.2.17
ATP
inhibits the reaction at high concentrations
2.4.2.17
Mg2+
at high concentrations, Ki = 23 mM
2.4.2.17
Mn2+
moderate inhibitory effect
2.4.2.17
ADP
competitive to ATP, in the presence of histidine inhibition by AMP and ADP becomes positively cooperative and much more potent
2.4.2.17
ADP
-
2.4.2.17
ADP
competitive to ATP
2.4.2.17
ADP
orthosteric inhibition
2.4.2.17
Zn2+
-
2.4.2.17
Zn2+
moderate inhibitory effect
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