EC Number   |
Inhibitors |
Structure |
|---|
   2.3.1.86 | 1,3-Dibromo-2-propanone |
- |
   |
| 2.3.1.86 | 1,3-Dibromo-2-propanone |
complete inhibition at 0.005 mM after 1 min, cross-links alpha-, not beta-subunits, inhibits only beta-ketoacyl synthetase reaction, acetyl-CoA prevents, malonyl-CoA prevents only slightly |
|
| 2.3.1.86 | 5,5'-dithio-bis(2-nitrobenzoic acid) |
covalent binding to palmitoyl residues, malonyl-CoA protects |
|
| 2.3.1.86 | 5,5'-dithio-bis(2-nitrobenzoic acid) |
- |
|
| 2.3.1.86 | cerulenin |
complete inhibition of type II fatty acid synthase at 0.1 mM |
|
| 2.3.1.86 | cerulenin |
- |
|
| 2.3.1.86 | iodoacetamide |
complete inhibition of type II fatty acid synthase at 1 mM |
|
| 2.3.1.86 | iodoacetamide |
beta-ketoacyl synthetase; no inhibition of acetyl transferase activity |
|
| 2.3.1.86 | iodoacetamide |
no inhibition of acetyl transferase activity; pH-independent between 5.0 and 9.0 |
|
| 2.3.1.86 | iodoacetamide |
irreversible |
|
