EC Number |
Inhibitors |
Structure |
---|
3.5.4.13 | dTTP |
inhibition of deamination reaction |
|
3.5.4.13 | dTTP |
inhibits by increasing the kcat several fold, mutants S111T and E138D are less sensitive to dTTP, overview |
|
3.5.4.13 | dTTP |
inhibits the enzyme in a nonallosterical way, cooperative kinetics are imposed by a dTTP-dependent lag of product formation observed in presteady-state kinetics, the lag may be derived from a slow equilibration between an inactive and an active conformation of dCTP deaminase represented by the dTTP complex and the dUTP/dCTP complex, respectively, steady-state kinetic analysis of dTTP inhibition, overview |
|
3.5.4.13 | dTTP |
the inhibitor has a regukatory function for the bifunctional enzyme, mechanism of regulation by conformational changes, overview |
|
3.5.4.13 | dTTP |
inhibits dCMP deamination, feedback inhibition |
|
3.5.4.13 | CDP |
- |
|
3.5.4.13 | dUTP |
- |
|
3.5.4.13 | dUTP |
inhibition of deamination reaction |
|
3.5.4.13 | dTDP |
- |
|
3.5.4.13 | dTMP |
- |
|