EC Number   |
Inhibitors |
Structure |
|---|
  1.1.1.112 | Dienstrol |
0.01 mM, oxidation of acenaphthenol: 27% inhibition of isozyme 1, 84% inhibition of isozyme 2, 99%,inhibition of isozyme 3, 94% inhibition of isozyme 4, 0% inhibition of isozyme 5, 66% inhibition of isozyme 6 and 0% inhibition of isoenzyme 7, oxidation of 5alpha-androstane-3alpha,17beta-diol: 27% inhibition of isozyme 1, 85% inhibition of isozyme 2, 99%,inhibition of isozyme 3, 97% inhibition of isozyme 4, 0% inhibition of isozyme 5, 51% inhibition of isozyme 6 and 0% inhibition of isoenzyme 7 |
   |
| 1.1.1.112 | diethylstilbestrol |
0.01 mM, oxidation of acenaphthenol: 25% inhibition of isozyme 1, 68% inhibition of isozyme 2, 94%,inhibition of isozyme 3, 90% inhibition of isozyme 4, 6% inhibition of isozyme 5, 44% inhibition of isozyme 6 and 44% inhibition of isoenzyme 7, oxidation of 5alpha-androstane-3alpha,17beta-diol: 23% inhibition of isozyme 1, 69% inhibition of isozyme 2, 87%,inhibition of isozyme 3, 99% inhibition of isozyme 4, 0% inhibition of isozyme 5, 49% inhibition of isozyme 6 and 47% inhibition of isoenzyme 7 |
|
| 1.1.1.112 | Flufenamic acid |
0.1 mM, oxidation of acenaphthenol: 54% inhibition of isozyme 1, 47% inhibition of isozyme 2, 64%,inhibition of isozyme 3, 60% inhibition of isozyme 4, 50% inhibition of isozyme 5, 57% inhibition of isozyme 6 and 38% inhibition of isoenzyme 7, oxidation of 5alpha-androstane-3alpha,17beta-diol: 46% inhibition of isozyme 1, 45% inhibition of isozyme 2, 47%,inhibition of isozyme 3, 49% inhibition of isozyme 4, 58% inhibition of isozyme 5, 46% inhibition of isozyme 6 and 43% inhibition of isoenzyme 7 |
|
| 1.1.1.112 | Hexestrol |
competitive inhibition vs. indanol |
|
| 1.1.1.112 | Hexestrol |
0.01 mM, oxidation of acenaphthenol: 76% inhibition of isozyme 1, 82% inhibition of isozyme 2, 95%,inhibition of isozyme 3, 87% inhibition of isozyme 4, 20% inhibition of isozyme 5, 50% inhibition of isozyme 6 and 72% inhibition of isoenzyme 7, oxidation of 5alpha-androstane-3alpha,17beta-diol: 66% inhibition of isozyme 1, 84% inhibition of isozyme 2, 90%,inhibition of isozyme 3, 85% inhibition of isozyme 4, 10% inhibition of isozyme 5, 50% inhibition of isozyme 6 and 77% inhibition of isoenzyme 7 |
|
| 1.1.1.112 | indomethacin |
0.1 mM, oxidation of acenaphthenol: 20% inhibition of isozyme 1, 49% inhibition of isozyme 2, 55%,inhibition of isozyme 3, 78% inhibition of isozyme 4, 64% inhibition of isozyme 5, 59% inhibition of isozyme 6 and 3% inhibition of isoenzyme 7 |
|
| 1.1.1.112 | Medroxyprogesterone acetate |
competitive inhibition vs. indanol |
|
| 1.1.1.112 | progesterone |
competitive inhibition vs. indanol |
|
| 1.1.1.112 | pyrazole |
1 mM, 39% inhibition |
|
| 1.1.1.112 | Zomepirac |
0.1 mM, oxidation of acenaphthenol: 69% inhibition of isozyme 1, 46% inhibition of isozyme 2, 71%,inhibition of isozyme 3, 78% inhibition of isozyme 4, 69% inhibition of isozyme 5, 72% inhibition of isozyme 6 and 56% inhibition of isoenzyme 7, oxidation of 5alpha-androstane-3alpha,17beta-diol: 70% inhibition of isozyme 1, 68% inhibition of isozyme 2, 68%,inhibition of isozyme 3, 56% inhibition of isozyme 4, 68% inhibition of isozyme 5, 71% inhibition of isozyme 6 and 66% inhibition of isoenzyme 7 |
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