EC Number |
Activating Compound |
Reference |
---|
6.4.1.1 | 2',3'-O-(2,4,6-trinitrophenyl) adenosine 5'-triphosphate |
allosteric activator of pyruvate carboxylase. The increase in activity between 2 mM and saturating MgATP is approximately 16fold |
713960 |
6.4.1.1 | acetoacetyl-CoA |
activation in decreasing order: acetyl-CoA, n-propanyl-CoA, n-butanoyl-CoA, malonyl-CoA/ CoA, acetoacetyl-CoA, oleoyl-CoA |
1760 |
6.4.1.1 | acetyl CoA |
activates |
649374 |
6.4.1.1 | acetyl CoA |
enzyme activator, major effect is to promote the carboxylation of biotin, reduces the Kms for both MgATP2- and biotin, overview |
692637 |
6.4.1.1 | acetyl-CoA |
- |
1766, 1769, 1781, 1792, 661386, 663285, 694325, 714190, 715211, 727019, 727040 |
6.4.1.1 | acetyl-CoA |
acetyl-CoA acts to decrease the activation free energy of the reaction by both increasing the activation entropy and decreasing the activation enthalpy |
744355 |
6.4.1.1 | acetyl-CoA |
activates |
1768, 1769, 1770, 1771, 1774, 1779 |
6.4.1.1 | acetyl-CoA |
activates in presence of either L-Asp or 2-oxoglutarate but does not activate in absence of these dicarboxylic acids. Trinitrobenzenesulfonate causes selective loss of the capacity for activation by acetyl-CoA |
1765 |
6.4.1.1 | acetyl-CoA |
activates phosphorylation of MgADP2- by carbamoyl phosphate |
1787 |
6.4.1.1 | acetyl-CoA |
activates Pyc1 at 0.25 mM |
650151 |